Zebinix: new for epilepsy

Zebinix (eslicarbazepine acetate) has been launched as an adjunctive treatment for partial-onset seizures with or without secondary generalisation.

Eslicarbazepine acetate is a carboxamide derivative.

The drug's exact mechanism of action is unknown, but it is suggested that it works by stabilising the inactivated state of voltage-gated sodium channels, preventing their return to the activated state therefore sustaining repetitive neuronal firing.

Zebinix must be added to existing anticonvulsant therapy and the dose increased gradually. Zebinix is licensed for the management of epilepsy in adults; caution should be exercised when managing elderly patients and it is not recommended for use in children.

View Zebinix drug record

Further information: Eisai

To sign up for the MIMS monthly news update, register at www.mims.co.uk/bulletins.

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Already registered?
Sign in

More from MIMS

An elderly woman with one arm in a plaster cast sits resting both hands on her walker

Doctors urge NICE to reverse decision on new osteoporosis drug

More than NHS 100 clinicians have called on NICE to...

Drug shortages - live tracker

Use our constantly updated shortages tracker to check...

Image of both strengths of Seffalair Spiromax inhaler side by side.

New salmeterol/fluticasone dry powder inhaler for asthma

Seffalair Spiromax is the sixth dry powder salmeterol/fluticasone...

An older man in a blue shirt and beige trousers leans forward on a sofa rubbing his painful lower back. Promoted

Established muscle relaxant offers new approach to managing back pain

Sponsored by Mibe Pharma

A muscle relaxant that has been used for decades outside the UK may provide an alternative to current treatments for low back pain, explains Dr Sunny Nayee, consultant in anaesthesia and pain medicine at Imperial College NHS Healthcare Trust.

Sponsored by Mibe Pharma UK Ltd. UK/MYO/21/044; December 2021.

Click here to view prescribing information for Myopridin® (pridinol mesilate)