Eslicarbazepine acetate is a carboxamide derivative.
The drug's exact mechanism of action is unknown, but it is suggested that it works by stabilising the inactivated state of voltage-gated sodium channels, preventing their return to the activated state therefore sustaining repetitive neuronal firing.
Zebinix must be added to existing anticonvulsant therapy and the dose increased gradually. Zebinix is licensed for the management of epilepsy in adults; caution should be exercised when managing elderly patients and it is not recommended for use in children.
Further information: Eisai
To sign up for the MIMS monthly news update, register at www.mims.co.uk/bulletins.