Blurred vision is an established side-effect of steroid treatment, and may be a symptom of cataract and glaucoma. In rare cases, however, it could indicate the presence of CSCR.
If a patient who has received corticosteroid treatment presents with visual symptoms, clinicians should consider referral to an ophthalmologist for evaluation of possible causes.
CSCR is characterised by the accumulation of subretinal fluid at the posterior pole of the fundus, ultimately causing retinal detachment. CSCR typically affects one eye only and can cause vision to be blurry and distorted, with objects often appearing smaller and distorted in the affected eye. Patients may also have difficulty with bright lights and contrast sensitivity.
Although the exact mechanism leading to the development of CSCR is unknown, several possible risk factors have been described, including use of systemic corticosteroids, pregnancy, and Cushing's syndrome. These risks are thought to be associated with the effect of cortisol on the eye.
CSCR has recently also been described after local administration of corticosteroids via inhaled and intranasal, epidural, intra-articular, topical dermal, and periocular routes.