The concentration of Tamiflu (oseltamivir) oral suspension has changed from 12mg per ml to 6mg per ml, with consequent changes in the dosing instructions.
The dispenser supplied with the revised product will measure in millilitres rather than in milligrams and Roche advises that all prescriptions for Tamiflu oral suspension should now state the dose in millilitres. Patients and parents/carers of children should be carefully advised of the changes.
Supplies of the old presentation expired at the end of July and stocks of the new 6mg per ml presentation are expected to become available in early October. Should the product be required in the interim period, Roche directs prescribers to sections 4.2 and 6.6 of the SPCs for Tamiflu Capsules, which describe the preparation of suitable dosage forms when the powder for suspension is unavailable.
Tamiflu is licensed for the treatment and prevention of influenza when the virus is circulating in the community.