Sporanox to be avoided in heart failure

The antifungal agent Sporanox (itraconazole) should not be used in patients with congestive heart failure or a history of congestive heart failure unless the benefit clearly outweighs the risk.

The warning follows observations that Sporanox exerts a negative inotropic effect, and reports of congestive heart failure associated with its use.

If the benefits do exceed the risk of using Sporanox in patients with heart failure, such patients should be monitored closely and the drug discontinued if symptoms of heart failure develop.

View Sporanox drug record

Further Information: Janssen-Cilag Ltd

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