Simeprevir in Combination with Peginterferon Alfa and Ribavirin for Treating Genotypes 1 and 4 Chronic Hepatitis C (TA331)

Technology Appraisal Guidance No. 331

Source: National Institute for Health and Care Excellence

1. Guidance

This guidance gives recommendations for simeprevir in combination with peginterferon alfa and ribavirin. Simeprevir also has a marketing authorisation for use in combination with sofosbuvir. Recommendations for simeprevir in combination with sofosbuvir will be developed in separate guidance.

1.1 Simeprevir, in combination with peginterferon alfa and ribavirin, is recommended within its marketing authorisation as an option for treating genotype 1 and 4 chronic hepatitis C in adults.

The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at http://guidance.nice.org.uk/TA331

This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.

© Copyright National Institute for Health and Care Excellence. All rights reserved. This material may be freely reproduced for educational and not for profit purposes within the NHS. No reproduction by or for commercial organisations is permitted without the express written permission of the Institute.

Enquiries concerning the guidance should be addressed to: National Institute for Health and Care Excellence, MidCity Place, 71 High Holborn, London WC1V 6NA. email: nice@nice.org.uk

Simeprevir in combination with peginterferon alfa and ribavirin for treating genotypes 1 and 4 chronic hepatitis C.

Issue Date: February 2015


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