Protopic prescribing information revised

The prescribing information for Protopic (tacrolimus) has been revised following an EMEA review of the safety and efficacy of topical calcineurin inhibitors.

Most of the changes are related to minimising the risk of developing malignancies, including cutaneous and other types of lymphomas when using Protopic to treat atopic dermatitis.

It is recommended that Protopic ointment is applied intermittently and not continuously, being discontinued when clearance occurs and re-initiated if symptoms recur.

Protopic should not be used in patients with congenital or acquired immunodeficiencies or in those being treated with immunosuppressants. Similarly, Protopic should not be applied to lesions considered to be potentially malignant or pre-malignant and care should be exercised when applying the ointment to large areas over prolonged periods.

Further information: Astellas Pharma Ltd, Lovett House, Lovett Road, Staines, Middlesex TW18 3AZ. Tel: (01784) 419615.

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

More from MIMS

Ophthalmic Preparations, Preservatives and Potential Sensitisers as Ingredients

Ophthalmic Preparations, Preservatives and Potential Sensitisers as Ingredients

Potential sensitising agents in eye drops and ointments.

Anti-Anginal Preparations, Summary by Pharmacological Class

Anti-Anginal Preparations, Summary by Pharmacological Class

Available formulations of anti-anginal drugs.

Researchers query safety of delaying antibiotics for UTI in elderly

Researchers query safety of delaying antibiotics for UTI in elderly

Delaying or withholding antibiotics for symptoms of...

Blood Glucose Testing Strips and Meters

Blood Glucose Testing Strips and Meters

Compatible test strips for blood glucose meters.