New name for Humalog insulin biosimilar

Admelog (insulin lispro) is a biosimilar of the rapid-acting insulin Humalog.

Graphic illustration of the Admelog prefilled SoloStar insulin pen, showing its pale yellow body, dosing window and the burgundy push button at the base.
Admelog (insulin lispro) is the first biosimilar of a rapid-acting insulin. | SANOFI

Previously marketed as Insulin Lispro Sanofi, Admelog is a 100iu/ml solution for injection available in the SoloStar pre-filled pen, as 3ml cartridges for the AllStar Pro and JuniorSTAR reusable pens, and in a vial for administration by syringe, intravenous injection or infusion pump.

As a biosimilar of Humalog, Admelog has a similar pharmacokinetic and pharmacodynamic profile to the originator product, with a rapid onset of action (approximately 15 minutes) and a shorter duration of activity (2–5 hours) than regular insulin.

Admelog produces a similar mean HbA1c reduction to Humalog in both type I and type II diabetes, and has a similar long-term safety and tolerability profile with comparable rates of hypoglycaemic events.

Admelog has 1:1 dose equivalence to Humalog, so no initial dose conversion is required.

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