Myopridin is indicated for central and peripheral muscle spasms including lumbar pain, torticollis and general muscle pain. The 3mg tablets are taken three times daily.
Used in Japan since 1967, pridinol has an atropine-like antispasmodic and muscle-relaxant action. It acts on alpha motor neurones in the spine to relieve skeletal muscle tension of both central and peripheral origin.
Pridinol relieves muscle tension more effectively the earlier treatment is started. In the case of long-standing muscle spasm, where anatomical changes have also occurred in the muscle fibres, ligaments and joint capsules, pridinol may only have a partial effect.
In an uncontrolled study in 1369 patients, adverse reactions to pridinol, including dry mouth, dizziness, headache, tachycardia and hypotension, were uncommon.