New muscle spasm treatment option

Myopridin (pridinol) can be prescribed to treat skeletal muscle tension of both central and peripheral origin.

 Pridinol is an antimuscarinic that acts on both smooth and striated muscles to relieve muscle spasm. | GETTY IMAGES
Pridinol is an antimuscarinic that acts on both smooth and striated muscles to relieve muscle spasm. | GETTY IMAGES

Myopridin is indicated for central and peripheral muscle spasms including lumbar pain, torticollis and general muscle pain. The 3mg tablets are taken three times daily.

Used in Japan since 1967, pridinol has an atropine-like antispasmodic and muscle-relaxant action. It acts on alpha motor neurones in the spine to relieve skeletal muscle tension of both central and peripheral origin.

Pridinol relieves muscle tension more effectively the earlier treatment is started. In the case of long-standing muscle spasm, where anatomical changes have also occurred in the muscle fibres, ligaments and joint capsules, pridinol may only have a partial effect.

In an uncontrolled study in 1369 patients, adverse reactions to pridinol, including dry mouth, dizziness, headache, tachycardia and hypotension, were uncommon.

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in