New indication for Tyverb

Tyverb (lapatinib) has had its licence extended to include use in combination with an aromatase inhibitor (AI), for the first-line treatment of post-menopausal women with hormone receptor (HR)-positive, ErbB2 (HER2)-overexpressing metastatic breast cancer for whom chemotherapy is not currently intended.

The registration trial showed that there was a significant improvement in progression-free survival (PFS) in patients overexpressing ErbB2 when both ErbB2 and HR receptors were targeted with lapatinib in combination with letrozole (an AI), with patients given lapatinib plus letrozole experiencing a median PFS of 8.2 months and patients given placebo plus letrozole experiencing a median PFS of 3 months.

View Tyverb drug record

Further information: GlaxoSmithKline

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

More from MIMS

Skin cancer warning for actinic keratosis treatment

Skin cancer warning for actinic keratosis treatment

Patients treated with ingenol mebutate (Picato) should...

Emollients, Potential Skin Sensitisers as Ingredients

Emollients, Potential Skin Sensitisers as Ingredients

Potential sensitising agents in emollient preparations.

Drug shortages - live tracker

Drug shortages - live tracker

Added: Accupro, Dermovate, Norinyl-1.
Use our...

Anti-Anginal Preparations, Summary by Pharmacological Class

Anti-Anginal Preparations, Summary by Pharmacological Class

Available formulations of anti-anginal drugs.