Malignancy contraindication for Regranex

Following a review by the European Medicines Agency, product information for the diabetic ulcer treatment becaplermin (Regranex) has been updated to include malignancy as a general contraindication.

The gel was previously contraindicated only in patients with skin cancer close to the application site.

In a retrospective study, patients who used three or more tubes of becaplermin had a 5.2 times greater risk of dying from cancer than matched controls, although their overall incidence of cancer was not increased.

View Regranex drug record

Further information: Janssen-Cilag

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