Lucentis - a new macular degeneration treatment

Novartis has launched Lucentis (ranibizumab) for the treatment of neovascular (wet) age-related macular degeneration.

Ranibizumab is a humanised recombinant monoclonal antibody fragment that targets human vascular endothelial growth factor A (VEGF-A). Ranibizumab prevents binding of VEGF-A to its receptors which leads to endothelial cell proliferation and neovascularisation, as well as vascular leakage, all of which are thought to contribute to the progression of the neovascular form of age-related macular degeneration.

Further information: Novartis 01276 692255

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