Iressa launched for lung cancer

Iressa (gefitinib) is a new treatment for locally advanced or metastatic non-small cell lung cancer with activating mutations of EGFR-TK.

Gefitinib is an antagonist of the epidermal growth factor receptor tyrosine kinase (EGFR-TK). In cancer cells, EGFR-TK-activating mutations contribute to cell survival, proliferation and metastasis.

Physicians should assess EGFR mutation status before administering gefinitib, as there is no evidence that the drug is effective in patients whose tumours lack EGFR mutations.

Interstitial lung disease is common in gefitinib-treated patients and can be severe; if this complication develops, the drug should be discontinued.

View Iressa drug record

Further information: AstraZeneca

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

More from MIMS

Sole of a foot with dry cracked skin on the heel.

New MIMS comparison table for urea-based emollients

Prescribers can now compare urea-based emollients with...

Drug shortages - live tracker

Use our constantly updated shortages tracker to check...

Logo of the webinar

Cow's Milk Allergy in Practice: free webinar series for UK healthcare professionals

Join us for a short webinar series offering insights...

Close up image of multicoloured capsules

MIMS antidepressants table updated

The MIMS table 'Antidepressants, a guide to switching...