Mecasermin is a human IGF-1 produced by recombinant DNA technology.
IGF–1 is the principal hormonal mediator of growth. In target tissues, IGF–1 activates the IGF–1 receptor, leading to intracellular signalling to induce and support statural growth. IGF–1 induces the uptake of glucose, fatty acids and amino acids so that metabolism supports growing tissues.
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