HPV vaccination schedule changes from three to two doses

The MIMS summary of routine childhood immunisations has been updated to reflect changes to the vaccination programme for human papillomavirus (HPV).

Gardasil should be administered by intramuscular injection, preferably into the deltoid area of the upper arm of the higher anterolateral area of the thigh
Gardasil should be administered by intramuscular injection, preferably into the deltoid area of the upper arm of the higher anterolateral area of the thigh

The vaccination schedule for HPV in secondary school girls aged 12–13 years has changed from three doses of Gardasil to two doses.

Research shows that the antibody response to the vaccine is as good for two doses as for three doses in the adolescent age group where efficacy against persistent infection and pre-cancerous lesions has been demonstrated. The first dose can be given at any time during school year 8, with a minimum of 6 months and a maximum of 24 months before the second dose.

Girls who have not had their first dose by the time they are 15 years old should be offered the three-dose schedule, as their antibody response is not as good as that in younger girls.

The changes to the schedule have been added to the MIMS routine childhood immunisation table in the September print edition, online and in the award-winning MIMS app.

Further information: Change in schedule from three to two doses in the HPV vaccination programme

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