Hepatitis C treatment in combination with amiodarone: risk of severe bradycardia

on the 24 August 2015

Patients receiving combination therapy with simeprevir (Olysio) and sofosbuvir (Sovaldi) should avoid concomitant use of amiodarone, unless other antiarrhythmics cannot be given.

Following the May issue of Drug Safety Update, the MHRA has extended its advice regarding the use of sofosbuvir combination therapy with amiodarone, to now include simeprevir.

Advice for monitoring patients receiving concomitant amiodarone and with cardiac rhythm disorders and hepatitis C can be found here.

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

The most up-to-date drug information at your fingertips.

  • Get the prescribing support you need.
  • Register today for full access to the MIMS database, plus tables and guideline summaries, new and deleted products and consultation tools.
Register Now
Already Registered?

Forgotten password?

MIMS Clinics

Prescribing news and resources for key therapeutic areas, collated by the MIMS editors.

Twitter  

More from MIMS

Ophthalmic Preparations, Preservatives and Potential Sensitisers as Ingredients

Ophthalmic Preparations, Preservatives and Potential Sensitisers as Ingredients

Potential sensitising agents in eye drops and ointments.

MIMS launches Respiratory and Allergy Learning workshops 2019

MIMS launches Respiratory and Allergy Learning workshops 2019

Join us for the MIMS Workshops Respiratory and Allergy...

Hormone Replacement Therapy (HRT)

Hormone Replacement Therapy (HRT)

Hormone doses and costs of HRT preparations.

Widespread false diagnosis of COPD is exposing patients to unnecessary medication risks, study suggests

Widespread false diagnosis of COPD is exposing patients to unnecessary medication risks, study suggests

Patients are being unnecessarily exposed to the adverse...