Pandemrix should be used in accordance with official guidance.
The dose recommendations are based on safety and immunogenicity data available from the administration of AS03-adjuvanted vaccine containing 3.75 microgram HA derived from A/Vietnam/1194/2004 (H5N1) in adults including the elderly. Half the dose was given to children 3-9 years old and doses were given on days 0 and 21.
Limited immunogenicity data suggest that a second dose may not be required in healthy adults aged 18-60 years.
Further information: GSK
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