Five cases of serious skin reactions, including Stevens-Johnson syndrome (SJS), acute generalised exanthematous pustulosis (AGEP) and erythema multiforme have been reported in patients taking galantamine.
Discontinue if rash occurs
Patients being treated with galantamine should be advised to discontinue treatment and seek medical help immediately if any of the following symptoms occur:
- severe rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (SJS).
- red rash covered with small pus-filled bumps that can spread over the body, sometimes with a fever (AGEP).
- rash that may blister, with spots that look like small targets (erythema multiforme).