Empagliflozin in Combination Therapy for Treating Type 2 Diabetes (TA336)

Technology Appraisal Guidance No. 336

Source: National Institute for Health and Care Excellence

1. Guidance

1.1 Empagliflozin in a dual therapy regimen in combination with metformin is recommended as an option for treating type 2 diabetes, only if:

  • a sulfonylurea is contraindicated or not tolerated, or
  • the person is at significant risk of hypoglycaemia or its consequences.

1.2 Empagliflozin in a triple therapy regimen is recommended as an option for treating type 2 diabetes in combination with:

  • metformin and a sulfonylurea or
  • metformin and a thiazolidinedione.

1.3 Empagliflozin in combination with insulin with or without other antidiabetic drugs is recommended as an option for treating type 2 diabetes.

1.4 People currently receiving treatment initiated within the NHS with empagliflozin that is not recommended for them by NICE in this guidance should be able to continue treatment until they and their NHS clinician consider it appropriate to stop.

The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at http://guidance.nice.org.uk/TA336

This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.

© Copyright National Institute for Health and Care Excellence. All rights reserved. This material may be freely reproduced for educational and not for profit purposes within the NHS. No reproduction by or for commercial organisations is permitted without the express written permission of the Institute.

Enquiries concerning the guidance should be addressed to: National Institute for Health and Care Excellence, MidCity Place, 71 High Holborn, London WC1V 6NA. email: nice@nice.org.uk

Empagliflozin in combination therapy for treating type 2 diabetes.

Issue Date: March 2015

 


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