Duloxetine may cause akathisia

on the 4 September 2006

Duloxetine, marketed under the brand names of Cymbalta and Yentreve, may be associated with the development of akathisia, characterised by restlessness and an inability to sit or stand still.

Doctors are advised that in patients who develop these symptoms increasing the dose may be detrimental and that it may be necessary to review the use of the drug. If therapy does need to be withdrawn, it should be done gradually.

Further information: Lilly, Lilly House, Priestley Road, Basingstoke, Hants RG24 9NL. Tel: (01256) 315000.
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