Cyanide antidote launched

1 October 2010

Cyanokit is an injectable preparation of hydroxocobalamin (vitamin B12) indicated for the treatment of known or suspected cyanide poisoning.

Hydroxocobalamin has a favourable safety profile in patients who have not been poisoned, making Cyanokit a useful option when cyanide exposure is unproven.

Cyanokit must be used alongside adequate supportive measures, including maintenance of airway patency, oxygen therapy, hydration, cardiovascular support and management of seizures.

Cyanide has a large number of industrial applications; poisoning with this substance typically occurs as a result of smoke inhalation or occupational exposure.

Hydroxocobalamin reacts with cyanide to form cyanocobalamin, which is eliminated in the urine.

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