COVID-19 vaccines

COVID-19 vaccines available in the UK.

Last updated 17th January 2022: added booster dose to Spikevax

COVID-19 Vaccines
NAMEMANUFACTURERPRESENTATIONTYPE OF VACCINEAGEDOSESTORAGE CONDITIONS

Comirnaty

BioNTech-Pfizer 

30 microgram/0.3ml conc for dispersion for inj in vial, 0.45ml

10 microgram/0.2ml conc for dispersion for inj in vial, 1.3ml

mRNA (nucleoside modified) encoding viral spike protein of SARS-CoV-2, embedded in lipid nanoparticles

From 5 years

From 12 years: 30 microgram/0.3ml by im inj, repeated after 21 days. A booster dose may be given ≥6 months after second dose in patients ≥18 years.

From 5 to 11 years, 10 microgram/0.2ml by im inj, repeated after 21 days.

Store frozen at -90oC to -60oC for ≤9 months.*

Can be stored refrigerated at 2oC to 8oC for ≤31 days then at ≤30oC for ≤2hrs.*

Following dilution store at 2oC to 30oC; use within 6 hrs.*

Vial should not be shaken.

Spikevax

Moderna Biotech

100 microgram/0.5ml dispersion for inj in vial, 5ml

mRNA (nucleoside modified) encoding viral spike protein of SARS-CoV-2, embedded in SM-102 lipid nanoparticles

From 12 years

0.5ml by im inj, repeated after ≥28 days. A booster dose of 0.25ml may be given ≥6 months after second dose in patients ≥18 years.

Store frozen at -25oC to -15oC for ≤9 months.

Can be stored refrigerated at 2oC to 8oC for ≤30 days then at 8oC to 25oC for ≤24 hrs. 

Following first withdrawal store at 2oC to 25oC; use within 6 hrs.

Vial should not be shaken.

Vaxzevria▼ 

AstraZeneca

Susp for inj in vial, 4ml or 5ml

Recombinant adenovirus vector encoding viral spike protein of SARS-CoV-2, 2.5 x 108 infectious units per 0.5ml

From 18 years

0.5ml by im inj, repeated after 4–12 weeks. A booster dose may be given ≥6 months after second dose.

Store refrigerated at 2oC to 8oC for ≤6 months.

Following first withdrawal store at 2oC to 25oC; use within 6 hrs.

Vial should not be shaken.

*Unbranded temporarily authorised COVID-19 Vaccine Pfizer/BioNTech (Regulation 174) should be stored frozen at -80°C to -60°C for ≤9 months and may be thawed at ≤25°C for ≤2hrs. Following dilution it should be stored at 2°C to 25°C and used within 6 hrs.

Notes

  • Once thawed vaccines cannot be re-frozen.
  • All vaccines should ideally be given into the deltoid muscle.
  • The Joint Committee on Vaccination and Immunisation (JCVI) has advised that pregnant women be offered COVID-19 vaccines at the same time as people of the same age or risk group. Comirnaty and Spikevax are the preferred first-dose vaccines for pregnant women of any age.1
  • The JCVI says that COVID-19 vaccines can be received whilst breastfeeding.1
  • Check national guidelines for any updates to dosing schedules, available at gov.uk.
  • Report any suspected adverse reactions to COVID-19 vaccines at coronavirus-yellowcard.mhra.gov.uk.

Information summarised from manufacturers' Summaries of Product Characteristics (SPCs), available at medicines.org.uk.

Reference:

  1. COVID-19 vaccination: a guide for all women of childbearing age, pregnant or breastfeeding (updated 14 June 2021).

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