Combination gel for scalp and body psoriasis

Dovobet Gel is a combined preparation of calcipotriol and betamethasone (50/500 microgram per gram), licensed for both scalp and body psoriasis. It is presented as a clear, alcohol-free gel.

Calcipotriol and betamethasone have complementary mechanisms of action in the treatment of psoriasis. Calcipotriol, a vitamin D analogue, is thought to inhibit keratinocyte proliferation; betamethasone, a corticosteroid, acts as an anti-inflammatory.

The combination gel was tested in randomised, double-blind studies in patients with body psoriasis (n=364) or scalp psoriasis (n=1,505). Response rates observed after the recommended duration of treatment (eight and four weeks, respectively) were significantly higher for the combination gel than for the calcipotriol, betamethasone or vehicle gels alone.

View Dovobet Gel drug record

Further information: Leo Pharma

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

More from MIMS

Drug shortages - live tracker

Drug shortages - live tracker

Check on the latest drug supply issues with MIMS' shortages...

Novel MS drug gains NICE approval

Novel MS drug gains NICE approval

New NICE guidance recommends ocrelizumab (Ocrevus)...

Emollients, Potential Skin Sensitisers as Ingredients

Emollients, Potential Skin Sensitisers as Ingredients

Potential sensitising agents in emollient preparations.

NICE recommends new triple therapy option for diabetes

NICE recommends new triple therapy option for diabetes

Ertugliflozin (Steglatro) can now be prescribed routinely...