Sugammadex is a modified gamma cyclodextrin, a selective relaxant binding agent. It forms a complex with the neuromuscular blocking agents rocuronium or vecuronium in plasma reducing the amount of neuromuscular blocking agent available to bind to nicotinic receptors in the neuromuscular junction. This results in the reversal of neuromuscular blockade induced by rocuronium or vecuronium.
Sugammadex should only be administered by, or under the supervision of, an anaesthetist.
Further information: Schering-Plough