Treatment comprises five injections and can be repeated every three months.
The efficacy of botulinum toxin in the treatment of moderate to severe glabellar lines was evaluated in a study of 537 patients.
Thirty days after treatment, investigators reported significant improvements in the appearance of glabellar lines at maximum frown in 80% of treated patients compared with 3% of those who received placebo.
When the appearance of glabellar lines was assessed by participants themselves, the corresponding figures were 89% and 7%, respectively.
Benefits were also seen among the 210 individuals who had glabellar lines at rest, with improvements noted in 74% of those who received botulinum toxin compared with 20% of those given placebo injections.
Further information: Allergan