Botox licensed for wrinkle reduction

Botox (botulinum toxin) has been licensed for the temporary improvement of moderate to severe glabellar lines, when they have an important psychological impact and the patient is <65 years old.

Botox is already licensed for use in certain types of muscle spasm and spasticity, hyperhidrosis and migraine
Botox is already licensed for use in certain types of muscle spasm and spasticity, hyperhidrosis and migraine

Treatment comprises five injections and can be repeated every three months.

The efficacy of botulinum toxin in the treatment of moderate to severe glabellar lines was evaluated in a study of 537 patients.

Thirty days after treatment, investigators reported significant improvements in the appearance of glabellar lines at maximum frown in 80% of treated patients compared with 3% of those who received placebo.

When the appearance of glabellar lines was assessed by participants themselves, the corresponding figures were 89% and 7%, respectively.

Benefits were also seen among the 210 individuals who had glabellar lines at rest, with improvements noted in 74% of those who received botulinum toxin compared with 20% of those given placebo injections.

View Botox drug record

Further information: Allergan

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