Ivermectin in rosacea

NICE has issued advice on the use of ivermectin cream for inflammatory lesions in papulopustular rosacea

In two RCTs, ivermectin 10mg/g cream was statistically significantly more effective than vehicle cream (placebo) in improving rosacea severity score and reducing inflammatory lesion count. 

In another RCT, ivermectin was superior to metronidazole cream at reducing lesion count and improving rosacea severity score, with study participants having about 10% fewer lesions. Local adverse events, including skin irritation, pruritus and dry skin, are common, although these are mostly transient, and mild to moderate in severity. 

More than two-thirds of patients using ivermectin rated their improvement as ‘excellent’ or ‘good’, compared with about one-third of people in the vehicle group.

ESNM68. London, NICE, January 2016

Want news like this straight to your inbox?
Sign up for our bulletins

Read these next

Genetics and environment in rosacea

Researchers in Cleveland, Ohio, have carried out a...

New topical treatment option for patients with rosacea

Galderma has launched Soolantra, a topical cream containing...

Case reports: Worsening facial redness with flushing episodes

Case reports: Worsening facial redness with flushing episodes

This patient presented with a red complexion, telangiectasia...

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Already registered?
Sign in

MIMS Product Slides

Product overviews prepared by the MIMS team, in a handy slide format.

Click here

Slides are initiated, funded & reviewed by the companies specified.

Register or Subscribe to MIMS

GPs can get MIMS print & online and GPonline for free when they register online – take 2 minutes, and make sure you get your free MIMS access! If you're not a GP, you can subscribe to MIMS for full access.

Register or subscribe

MIMS Dermatology

Read the latest issue online exclusively on MIMS Learning.

Read MIMS Dermatology

MIMS Adviser

Especially created for prescribing influencers.

Request free copy

Mobile apps

MIMS: access the full drug database and quick-reference tables on the go

MIMS Diagnosis and Management: concise information on signs and symptoms, investigations and diseases