This study assessed Staph aureus colonisation in 40 patients with NE and 40 healthy close contacts who had swabs taken for Staph aureus from the skin, anterior nares and right second subungual space.
The results showed higher rates of colonisation for Staph aureus and MRSA in patients with NE compared to healthy close contacts. The anterior nares and subungual spaces were the main reservoirs for self-contamination and recolonisation. Patients with severe NE had higher rates of colonisation and toxin genes.
The researchers advise that patients should try to reduce nasal and subungual colonisation and conclude there is a link between NE disease severity and Staph aureus colonisation, but more research is needed.
Kim BS, Kim WJ, Ko HC et al. Br J Dermatol 2012; May 25