Emollients and skin barrier function

on the 26 October 2011

A small study has found that Aqueous Cream BP can cause damage to the skin barrier in patients with a predisposition to atopic dermatitis and should therefore not be used as a leave-on emollient in such cases

The authors applied Aqueous Cream BP twice daily to the forearms of 13 volunteers for four weeks. They found that its application resulted in significant increase in transepidermal water loss and decrease in integrity of the stratum corneum. Aqueous Cream BP therefore negatively affected the skin barrier, which could lead to disease flares.
Danby SG, Al-Enezi T, Sultan A et al. Br J Dermatol 2011; 165: 329-34
Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

The most up-to-date drug information at your fingertips.

  • Get the prescribing support you need.
  • Register today for full access to the MIMS database, plus tables and guideline summaries, new and deleted products and consultation tools.
Register Now
Already Registered?

Forgotten password?

MIMS Clinics

Prescribing news and resources for key therapeutic areas, collated by the MIMS editors.

Twitter  

More from MIMS

Two new steroid inhalers launched

Two new steroid inhalers launched

A new beclometasone metered-dose inhaler and a new...

Half of patients on statins do not reach cholesterol goals, study shows

Half of patients on statins do not reach cholesterol goals, study shows

Half of patients prescribed statins fail to reach their...

First oral hypoglycaemic licensed for add-on therapy in type I diabetes

First oral hypoglycaemic licensed for add-on therapy in type I diabetes

The SGLT2 inhibitor dapagliflozin (Forxiga) can now...

Quick-reference MIMS COPD prescribing resources updated

Quick-reference MIMS COPD prescribing resources updated

Concise MIMS resources on COPD management and antibiotic...