Family history and risk of melanoma

Studies have reported on the association between family history and increased risk of melanoma, but few have reported on familial mortality in melanoma

Here, researchers investigated familial risks for incident and fatal melanoma using the Swedish Family Cancer Database to calculate standardised incidence ratios for incident melanoma for relatives of cancer patients and standardised mortality ratios for death from melanoma for relatives of those who had died of cancer. They found a familial clustering of fatal melanoma between parents and offspring. Familial incidence and familial mortality were equal. A pattern of familial incidence of melanoma and oesophageal, colorectal, breast, prostate, kidney, nervous system cancers and myeloma and leukaemia was noted.
Brandt A, Sundquist J, Hemminki K et al. Br J Dermatol 2011; 165: 342-8

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