In a randomised double-blind placebo-controlled study, 120 women with PMS were randomly assigned to receive 1g or 2g of a combination of gamma linolenic acid, oleic acid, linoleic acid, other polyunsaturated acids and vitamin E, or placebo.
The researchers recorded symptoms over a six-month period and measured total cholesterol and prolactin levels. Women who received the 1g capsule experienced significant decreases in menstrual symptoms at three and six months compared with baseline; this reduction was greater in women who received the 2g capsule.
Rocha Filho E, Lima JC, Pinho Neto J et al. Reprod Health 2011; 8: 2