The investigators measured alpha-tocopherol concentration in adipose tissue samples from 8 children for up to a year after a severe burn injury.
At 2 and 3 weeks after the injury, alpha-tocopherol concentrations (which represent vitamin E status) were substantially decreased.
Linear regression analysis revealed that individual adipose tissue alpha-tocopherol concentration decreased by 6.1 +/- 0.6 nmol/g daily. Further studies are needed to elucidate the mechanism of this vitamin E depletion and the consequences for the patient.
Traber MG, Leonard SW, Traber DL et al. Am J Clin Nut 2010