Afinitor licensed for pancreatic tumours

1 November 2011

Dosing is the same for all current indications: 10mg once daily

Afinitor (everolimus) is now indicated for the treatment of advanced pancreatic neuroendocrine tumours in patients with unresectable or metastatic disease.

In the randomised, double-blind study, RADIANT-3 (n=410), median progression-free survival more than doubled with everolimus compared with placebo (11.0 vs 4.6 months).

Afinitor is also indicated for use in advanced renal cell carcinoma which has progressed during or after VEGF-targeted therapy. In addition, Novartis are launching everolimus as Votubia for the treatment of astrocytoma.

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