The metered-dose inhaler is available in two strengths:
- 25/125 (salmeterol 25 microgram, fluticasone propionate 125 microgram)
- 25/250 (salmeterol 25 microgram, fluticasone propionate 250 microgram)
Sirdupla can be used in patients over 18 years of age not adequately controlled with inhaled corticosteroids and an 'as needed' inhaled short-acting β2-agonist, and in those already adequately controlled on both an inhaled corticosteroid and a long-acting β2-agonist.
The efficacy and safety of salmeterol and fluticasone for the treatment of asthma are well established.
Prescribers should note that only the AeroChamber Plus spacer device should be used with Sirdupla.