Technology Appraisal Guidance No. 331
Source: National Institute for Health and Care Excellence
This guidance gives recommendations for simeprevir in combination with peginterferon alfa and ribavirin. Simeprevir also has a marketing authorisation for use in combination with sofosbuvir. Recommendations for simeprevir in combination with sofosbuvir will be developed in separate guidance.
1.1 Simeprevir, in combination with peginterferon alfa and ribavirin, is recommended within its marketing authorisation as an option for treating genotype 1 and 4 chronic hepatitis C in adults.
The guidance shown above constitutes Section 1 of the full document. A copy of the full document and a summary of the evidence is available on the Internet at http://guidance.nice.org.uk/TA331
This guidance represents the view of the Institute which was arrived at after careful consideration of the available evidence. Health professionals are expected to fully take it into account when exercising their clinical judgement. This guidance does not, however, override the individual responsibility of health professionals to make appropriate decisions in the circumstances of the individual patient, in consultation with the patient and/or guardian or carer.
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Simeprevir in combination with peginterferon alfa and ribavirin for treating genotypes 1 and 4 chronic hepatitis C.
Issue Date: February 2015