NICE endorses use of sofosbuvir-velpatasvir in chronic hepatitis C

Sofosbuvir-velpatasvir has been recommended by NICE as an option for treating chronic hepatitis C in adults, with specific recommendations made according to patients' HCV genotype, liver disease stage and treatment history.

NICE recommends that the decision to treat and prescribing decisions are made by multidisciplinary teams in the operational delivery networks put in place by NHS England, to prioritise treatment for people with the highest unmet clinical need.

The combination therapy, available in the UK as Epclusa, must be provided by the company in accordance with the simple discount agreement. Patients already being treated with the drug may continue without change according to whatever funding arrangements were in place before the guidance was issued until they and their NHS clinician consider it appropriate to stop.

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