Januvia (sitagliptin) can now be prescribed as an add-on to insulin (with or without metformin) for patients with type II diabetes in whom diet and exercise, plus a stable dose of insulin, do not provide adequate glycaemic control. In a 24-week study in 305 patients, addition of sitagliptin to insulin significantly improved glycaemic parameters compared with placebo, with no major effect on body weight. When Januvia is combined with insulin, reduction of the insulin dose may be appropriate to reduce the risk of hypoglycaemia.
View Januvia drug record
Further information: MSD
Januvia approved as add-on to insulin treatment
04 January 2010, 09:24am
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