Gardasil two-dose schedule approved

The human papillomavirus (HPV) vaccine Gardasil can now be administered in a two-dose schedule in children aged nine to 13 years for the prevention of premalignant cervical, vulvar and vaginal lesions, cervical cancer and external genital warts.

HPV vaccination coverage rates in England are among the highest in the world | SCIENCE PHOTO LIBRARY
HPV vaccination coverage rates in England are among the highest in the world | SCIENCE PHOTO LIBRARY

The licence for the quadrivalent HPV vaccine was extended following the results of a Canadian study that showed a two-dose schedule produced a non-inferior immunogenic response in girls aged 9-13 years to a three-dose course in women aged 16-26 years for the HPV-16 and HPV-18 genotypes. 

UK schedule to change in September

The routine childhood immunisation schedule produced by Public Health England will be updated in September. Until then, girls in the UK should continue to receive three doses of Gardasil between the ages of 12 and 13 years.

View Gardasil drug record


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