Botox licensed for wrinkle reduction

Botox (botulinum toxin) has been licensed for the temporary improvement of moderate to severe glabellar lines, when they have an important psychological impact and the patient is <65 years old.

Botox is already licensed for use in certain types of muscle spasm and spasticity, hyperhidrosis and migraine
Botox is already licensed for use in certain types of muscle spasm and spasticity, hyperhidrosis and migraine

Treatment comprises five injections and can be repeated every three months.

The efficacy of botulinum toxin in the treatment of moderate to severe glabellar lines was evaluated in a study of 537 patients.

Thirty days after treatment, investigators reported significant improvements in the appearance of glabellar lines at maximum frown in 80% of treated patients compared with 3% of those who received placebo.

When the appearance of glabellar lines was assessed by participants themselves, the corresponding figures were 89% and 7%, respectively.

Benefits were also seen among the 210 individuals who had glabellar lines at rest, with improvements noted in 74% of those who received botulinum toxin compared with 20% of those given placebo injections.

View Botox drug record

Further information: Allergan

Want news like this straight to your inbox?
Sign up for our bulletins

Have you registered with us yet?

Register now to enjoy more articles and free email bulletins

Register
Already registered?
Sign in

Register or Subscribe to MIMS

GPs can get MIMS print & online and GPonline for free when they register online – take 2 minutes, and make sure you get your free MIMS access! If you're not a GP, you can subscribe to MIMS for full access.

Register or subscribe

MIMS Dermatology

Read the latest issue online exclusively on MIMS Learning.

Read MIMS Dermatology

MIMS Adviser

Especially created for prescribing influencers.

Request free copy

Mobile apps

MIMS: access the full drug database and quick-reference tables on the go

MIMS Diagnosis and Management: concise information on signs and symptoms, investigations and diseases