Patient outcome measure for vitiligo

Researchers in the UK have published a study validating a new patient-reported outcome measure for response to treatment in vitiligo

The Vitiligo Noticeability Scale (VNS) asks patients to rate how noticeable their vitiligo is after treatment. 

In this validity study, patients and clinicians examined image pairs depicting simulated vitiligo pre- and post-treatment. They rated them for ‘noticeability’ and treatment success, and clinicians also estimated percentage repigmentation of lesions. Agreement between the responses was then assessed.

VNS scores were associated with both patient- and clinician-reported treatment success (kappa = 0.54 and 0.47, respectively), while percentage repigmentation showed a weaker correlation (k = 0.39 and 0.29, respectively). 

The researchers conclude that the VNS is a more consistent indicator of treatment success than percentage repigmentation, and VNS scores of four or five (out of five) represent success. 

This study focused on ‘high-expression’ sites (face and hands), but the researchers suggest that further large studies could assess the VNS on a wider range of anatomical sites.  

Batchelor JM, Tan W, Tour S et al. Br J Dermatol 2016; 174: 386-94

MIMS Clinics

Prescribing news and resources for key therapeutic areas, collated by the MIMS editors.

Register or Subscribe to MIMS

GPs can get MIMS print & online and GPonline for free when they register online – take 2 minutes, and make sure you get your free MIMS access! If you're not a GP, you can subscribe to MIMS for full access.

Register or subscribe

MIMS bulletins

News and updates straight to your inbox.

Prescribing Update: Fortnightly news bulletin
Urgent prescribing updates
Spotlight: Disease-themed monthly round-up

Sign me up

MIMS Dermatology

Read the latest issue online exclusively on MIMS Learning.

Read MIMS Dermatology

Mobile apps

MIMS: access the full drug database and quick-reference tables on the go

MIMS Diagnosis and Management: concise information on signs and symptoms, investigations and diseases

Promo Image

Clinical calculators

Handy calculators and conversions for primary care.