Inflammatory bowel disease and melanoma

Patients with inflammatory bowel disease (IBD) have an increased risk of melanoma and non-melanoma skin cancer (NMSC), according to US researchers

The study analysed the retrospective cohort and nested case-control studies to quantify the risk and how medications such as biologics affect this risk. Patients with Crohn's disease had a higher incidence of both melanoma and NMSC. Patients with IBD who were on biologics had a higher risk of melanoma, while those taking thiopurines had an increased risk of NMSC. The authors state that the increased risk is due to the immunosuppression of patients with IBD and recommend skin cancer surveillance and counselling of all patients with IBD.
Long MD, Martin C, Pipkin CA et al. Gastroenterology 2012

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