Risk of metastasis in melanoma

Results from a recent population-based cohort study have revealed that female melanoma patients have a lower risk of metastasis compared to males, and better survival

This study aimed to investigate differences in survival between genders for 11,744 cases of cutaneous melanoma taken from the Munich Cancer Registry.
The main outcome measures were survival, regional and systemic progression, and survival after progression.

The study showed the women had higher melanoma specific survival, were at lower risk of disease progression and had significant survival advantage after first progression. There was a lower risk of metastasis in women with localised melanoma than in men.
Joosee A, de Vries E, Eckel R et al. J Invest Dermatol 2011; 131: 719-26

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