Lipid Modification for the Prevention of Cardiovascular Disease

Adapted from NICE: Lipid modification - Cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease. May 2008.

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BOX 1
Clinical Assessment BP BMI Fasting blood glucose Renal function Liver function TSH if dyslipidaemia is present Smoking status Alcohol consumption Fasting TC, LDL-C, HDL-C and triglycerides (if not already available)	Lifestyle Advice Diet and weight Physical activity Alcohol reduction Smoking cessation

BOX 1

Clinical Assessment

BP
BMI
Fasting blood glucose
Renal function
Liver function
TSH if dyslipidaemia is present
Smoking status
Alcohol consumption
Fasting TC, LDL-C, HDL-C and triglycerides (if not already available)

Lifestyle Advice

Diet and weight
Physical activity
Alcohol reduction
Smoking cessation

BOX 2: FRAMINGHAM
CVD risk = 10-year risk of fatal and non-fatal stroke, including transient ischaemic attack + 10-year risk of CHD^‡ ^‡ CHD risk includes the risks of death from CHD, and non-fatal CHD, including silent MI, angina and coronary insufficiency (acute coronary syndrome). Notes: The Framingham equations should not be used for people already considered at high risk of CVD – use clinical assessment instead. The Framingham equations may overestimate risk in UK populations. Framingham CHD risk calculator available at www.mims.co.uk

BOX 2: FRAMINGHAM

CVD risk = 10-year risk of fatal and non-fatal stroke, including transient ischaemic attack + 10-year risk of CHD^‡

^‡ CHD risk includes the risks of death from CHD, and non-fatal CHD, including silent MI, angina and coronary insufficiency (acute coronary syndrome).

Notes: The Framingham equations should not be used for people already considered at high risk of CVD – use clinical assessment instead. The Framingham equations may overestimate risk in UK populations.

Framingham CHD risk calculator available at www.mims.co.uk

Full NICE guideline